Huger, Francis P.: search on Z-Library

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1

Synthesis and neuroleptic activity of 3-(1-substituted-4-piperidinyl)-1,2-benzisoxazoles

Strupczewski, Joseph T., Allen, Richard C., Gardner, Beth Ann, Schmid, Blaine L., Stache, Ulrich, Glamkowski, Edward J., Jones, Michael C., Ellis, Daniel B., Huger, Francis P., Dunn, Robert W.

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 1.11 MB

english, 1985

2

4-aminopyridine derivatives: A family of novel modulators of voltage-dependent sodium channels

Lei Tang, Francis P. Huger, Joseph T. Klein, Larry Davis, Lawrence L. Martin, Stephen Shimshock, Richard C. Effland, Craig P. Smith, Sathapana Kongsamut

Journal:

Drug Development Research

Year:

1998

Language:

english

File:

PDF, 105 KB

english, 1998

3

(.+-.)-9-Amino-1,2,3,4-tetrahydroacridin-1-ol. A potential Alzheimer's disease therapeutic of low toxicity

Shutske, Gregory M., Pierrat, Frank A., Cornfeldt, Michael L., Szewczak, Mark R., Huger, Francis P., Bores, Gina M., Haroutunian, Vahram, Davis, Kenneth L.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 281 KB

english, 1988

4

Synthesis and biological evaluation of a series of substituted N-alkoxyimides and -amides as potential atypical antipsychotic agents

Hrib, Nicholas J., Jurcak, John G., Huger, Francis P., Errico, Cheri L., Dunn, Robert W.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 671 KB

english, 1991

5

Substituted (Pyrroloamino)pyridines: Potential Agents for the Treatment of Alzheimer's Disease

Davis, Larry, Klein, Joseph T., Kapples, Kevin J., Huger, Francis P., Smith, Craig P., Petko, Wayne W., Cornfeldt, Michael, Effland, Richard C.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 172 KB

english, 1996

6

9-Amino-1,2,3,4-tetrahydroacridine-1-ol (HP 029) analogues: acetylcholinesterase and amine uptake inhibitory properties

ELLIS, DANIEL B., BORES, GINA M., SHUTSKE, GREGORY M., HUGER, FRANCIS P.

Journal:

Biochemical Society Transactions

Year:

1989

Language:

english

File:

PDF, 268 KB

english, 1989

7

Synthesis and Evaluation of 5-Amino-5,6,7,8-tetrahydroquinolinones as Potential Agents for the Treatment of Alzheimer's Disease

Fink, David M., Bores, Gina M., Effland, Richard C., Huger, Francis P., Kurys, Barbara E., Rush, Douglas K., Selk, David E.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 944 KB

english, 1995

8

Synthesis of 3-aryl-6H-isoxazolo[3,4-d]pyrazolo[3,4-b]pyridines and 3-aryl-6H-isoxazolo[5,4-d]pyrazolo[3,4-b]pyridines

Gregory M. Shutske, Francis P. Huger

Journal:

Journal of Heterocyclic Chemistry

Year:

1988

File:

PDF, 366 KB

1988

9

Tetrodotoxin inhibition in vitro of protoveratrine A-activated glutamate decarboxylase in synaptosomes

Francis P. Huger, Barry I. Gold

Journal:

Biochemical Pharmacology

Year:

1980

Language:

english

File:

PDF, 264 KB

english, 1980

10

Synthesis and in vitro acetylcholinesterase inhibitory activity of some 1-substituted analogues of velnacrine

Kevin J. Kapples, Gregory M. Shutske, Gina M. Bores, Francis P. Huger

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 277 KB

english, 1993

11

Aminopyridine carbamic acid esters: Synthesis and potential as acetylcholinesterase inhibitors and acetylcholine releasers

Gregory M. Shutske, John D. Tomer, Kevin J. Kapples, Nicholas J. Hrib, John G. Jurcak, Gina M. Bores, Francis P. Huger, Wayne Petko, Craig P. Smith

Journal:

Journal of Pharmaceutical Sciences

Year:

1992

Language:

english

File:

PDF, 707 KB

english, 1992

12

Effect of zinc on [3H]-QNB displacement by cholinergic agonists and antagonists

Craig P. Smith, Francis P. Huger

Journal:

Biochemical Pharmacology

Year:

1983

Language:

english

File:

PDF, 156 KB

english, 1983

13

Vascular and cardiac effects of HP 406 and nifedipine in vitro and in conscious spontaneously hypertensive rats and renal hypertensive dogs

John W. Hubbard, Joan F. Kapples, Scott T. Nordstrom, Laura C. Matson, Sandy J. Wilson, Rudyard J. Ress, Raymond W. Kosley Jr., Robert J. Cherill, Francis P. Huger, Stuart Fielding

Journal:

Drug Development Research

Year:

1988

Language:

english

File:

PDF, 804 KB

english, 1988

14

HP 749 enhances calcium-independent release of [3H]norepinephrine from rat cortical slices and synaptosomes

Craig P. Smith, Francis P. Huger, Wayne Petko, Sathapana Kongsamut

Journal:

Neurochemical Research

Year:

1994

Language:

english

File:

PDF, 497 KB

english, 1994

15

Adenylate Cyclase Stimulation and Intraocular Pressure Reduction by Forskolin Analogs

CAPRIOLI, JOSEPH, SEARS, MARVIN, MEAD, ALDEN, KOSLEY, RAYMOND W., CHERILL, ROBERT J., HUGER, FRANCIS P., ALLEN, RICHARD C., TRESSLER, CHARLES

Journal:

Journal of Ocular Pharmacology and Therapeutics

Year:

1989

Language:

english

File:

PDF, 516 KB

english, 1989

16

Pharmacological evaluation of HP 370, a potential atypical antipsychotic agent: 2. In vitro profile

Francis P. Huger, Craig P. Smith, Yulin Chiang, Edward J. Glamkowski, Daniel B. Ellis

Journal:

Drug Development Research

Year:

1987

Language:

english

File:

PDF, 456 KB

english, 1987

17

N-(n-propyl)-n-(3-fluoro-4-pyridinyl)-1h-3-methylindol-1-amine hydrochloride (HP 184): In vitro spontaneous release of acetylcholine and norepinephrine

Craig P. Smith, Linda R. Brougham, Francis P. Huger, Larry Davis, Joseph T. Klein, Richard C. Effland

Journal:

Drug Development Research

Year:

1993

Language:

english

File:

PDF, 915 KB

english, 1993

18

Mechanisms for the increase in electrically stimulated [3H]norepinephrine release from rat cortical slices by N-(n-propyl)-N-(4-pyridinyl)-1H-indol-1-amine

Craig P. Smith, Wayne W. Petko, Sathapana Kongsamut, Joachim E. Roehr, Richard C. Effland, Joseph T. Klein, Francis P. Huger

Journal:

Drug Development Research

Year:

1994

Language:

english

File:

PDF, 541 KB

english, 1994

19

Imino 1,2,3,4-tetrahydrocyclopent[b]indole carbamates as dual inhibitors of acetylcholinesterase and monoamine oxidase

David M. Fink, M.G. Palermo, Gina M. Bores, Francis P. Huger, Barbara E. Kurys, Michael C. Merriman, Gordon E. Olsen, Wayne Petko, Gerard J. O'Malley

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 346 KB

english, 1996

20

Synthesis and biological activity of putative mono-hydroxylated metabolites of velnacrine

Gregory M. Shutske, Gina M. Bores, Katherine C. Bradshaw, Francis P. Huger, Kevin J. Kapples, Raymond D. Larsen, Douglas K. Rush, John D. Tomer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1992

Language:

english

File:

PDF, 502 KB

english, 1992

21

Synthesis and Structure−Activity Relationships of N-Propyl-N-(4-pyridinyl)-1H-indol-1-amine (Besipirdine) and Related Analogs as Potential Therapeutic Agents for Alzheimer's Disease1

Klein, Joseph T., Davis, Larry, Olsen, Gordon E., Wong, George S., Huger, Francis P., Smith, Craig P., Petko, Wayne W., Cornfeldt, Michael, Wilker, Jeffrey C., Blitzer, R. D.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 385 KB

english, 1996

22

Calcium-stimulated glutamate decarboxylase activity in brain slices

Barry I. Gold, Francis P. Huger

Journal:

Biochemical Pharmacology

Year:

1982

Language:

english

File:

PDF, 364 KB

english, 1982

23

Synthesis of 5-phenylpyrrolo[1,2-b][1,2,5]-triazepin-2(3H)-ones

R. Richard L. Hamer, Richard C. Effland, Joseph T. Klein, Francis P. Huger, Jeffrey C. Wilker

Journal:

Journal of Heterocyclic Chemistry

Year:

1988

File:

PDF, 290 KB

1988

24

9-Amino-1,2,3,4-tetrahydroacridin-1-ols. Synthesis and evaluation as potential Alzheimer's disease therapeutics

Shutske, Gregory M., Pierrat, Frank A., Kapples, Kevin J., Cornfeldt, Michael L., Szewczak, Mark R., Huger, Francis P., Bores, Gina M., Haroutunian, Vahram, Davis, Kenneth L.

Journal:

Journal of Medicinal Chemistry

Year:

1989

Language:

english

File:

PDF, 1.21 MB

english, 1989

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